Wizard of Vitamins

Pyruvate Vitamin

What is Pyruvate?

Pyruvate (the buffered form of pyruvic acid) is a product created in the body during the metabolism of carbohydrates and protein.

Pyruvate in Diets

Pyruvate is formed in the body as a byproduct of the normal metabolism of carbohydrates and protein and is present in several foods, including red apples, cheese, dark beer, and red wine. Dietary supplements of pyruvate are also available.

Pyruvate Medicinal Treatments

Weight loss and obesity Athletic performance (for exercise performance) Athletic performance (for improving body composition with strength training in untrained people only)

Known Consequences of Pyruvate Deficiency

Because it is not an essential nutrient, pyruvate is not associated with a deficiency state.

Pyruvate Recommended Dosages

Most human research with pyruvate and weight loss has used at least 30 grams per day. However, such large amounts may not be necessary. In a six-week double-blind trial, as little as 6 grams per day of pyruvate in combination with exercise, led to greater weight loss and loss of body fat, compared with a placebo plus exercise.

Pyruvate Side Effects

High intakes of pyruvate can trigger gastrointestinal upset, such as gas, bloating, and diarrhea. One preliminary study in exercising women found 10 grams per day of pyruvate reduced blood levels of HDL (the “good” cholesterol) after one month. At the time of writing, there were no well-known drug interactions with pyruvate.